The tyrosine phosphatase Shp‐2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration

The Src homology‐2 domain‐containing tyrosine phosphatase 2 (SHP‐2) regulates many cellular processes, including proliferation, differentiation and survival. Polymorphisms in the gene encoding SHP‐2 are associated with an increased susceptibility to develop ulcerative colitis. We recently reported t...

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Detaylı Bibliyografya
Yayımlandı:J Pathol
Asıl Yazarlar: Gagné‐Sansfacon, Jessica, Langlois, Ariane, Langlois, Marie‐Josée, Coulombe, Geneviève, Tremblay, Sarah, Vaillancourt‐Lavigueur, Vanessa, Qu, Cheng‐Kui, Menendez, Alfredo, Rivard, Nathalie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Ltd 2018
Konular:
Original Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519201/
https://ncbi.nlm.nih.gov/pubmed/30376595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5177
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