SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development

A major risk factor of developing colorectal cancer (CRC) is the presence of chronic inflammation in the colon. In order to understand how inflammation contributes to CRC development, the present study focused on SHP-2, a tyrosine phosphatase encoded by PTPN11 gene in which polymorphisms have been s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Gagné-Sansfaçon, Jessica, Coulombe, Geneviève, Langlois, Marie-Josée, Langlois, Ariane, Paquet, Marilene, Carrier, Julie, Feng, Gen-Sheng, Qu, Cheng-Kui, Rivard, Nathalie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323184/
https://ncbi.nlm.nih.gov/pubmed/27582544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11601
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia