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Arylfluorosulfate‐Based Electrophiles for Covalent Protein Labeling: A New Addition to the Arsenal

Selective covalent modification of a targeted protein is a powerful tool in chemical biology and drug discovery, with applications ranging from identification and characterization of proteins and their functions to the development of targeted covalent inhibitors. Most covalent ligands contain an aff...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Martín‐Gago, Pablo, Olsen, Christian A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518939/
https://ncbi.nlm.nih.gov/pubmed/30024079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201806037
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