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Arylfluorosulfate‐Based Electrophiles for Covalent Protein Labeling: A New Addition to the Arsenal

Selective covalent modification of a targeted protein is a powerful tool in chemical biology and drug discovery, with applications ranging from identification and characterization of proteins and their functions to the development of targeted covalent inhibitors. Most covalent ligands contain an aff...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Angew Chem Int Ed Engl
Egile Nagusiak: Martín‐Gago, Pablo, Olsen, Christian A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518939/
https://ncbi.nlm.nih.gov/pubmed/30024079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201806037
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