Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

In sickle cell disease (SCD), sickle hemoglobin (HbS) polymerizes upon deoxygenation, resulting in sickling of red blood cells (RBCs). These sickled RBCs have strongly reduced deformability, leading to vaso‐occlusive crises and chronic hemolytic anemia. To date, there are no reliable laboratory para...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Am J Hematol
Main Authors: Rab, Minke A.E., van Oirschot, Brigitte A., Bos, Jennifer, Merkx, Tesy H., van Wesel, Annet C.W., Abdulmalik, Osheiza, Safo, Martin K., Versluijs, Birgitta A., Houwing, Maite E., Cnossen, Marjon H., Riedl, Jurgen, Schutgens, Roger E.G., Pasterkamp, Gerard, Bartels, Marije, van Beers, Eduard J., van Wijk, Richard
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518936/
https://ncbi.nlm.nih.gov/pubmed/30784099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25443
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker