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Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency
Heterogeneous expression of the transcription factor NANOG has been linked to the existence of various functional states in pluripotent stem cells. This heterogeneity seems to arise from fluctuations of Nanog expression in individual cells, but a thorough characterization of these fluctuations and t...
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| Veröffentlicht in: | Development |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517831/ https://ncbi.nlm.nih.gov/pubmed/25005472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108910 |
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