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Generation and Characterization of a Novel Mouse Embryonic Stem Cell Line with a Dynamic Reporter of Nanog Expression

BACKGROUND: The pluripotent state in embryonic stem (ES) cells is controlled by a core network of transcription factors that includes Nanog, Oct4 and Sox2. Nanog is required to reach pluripotency during somatic reprogramming and is the only core factor whose overexpression is able to oppose differen...

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Hlavní autoři: Abranches, Elsa, Bekman, Evguenia, Henrique, Domingos
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602340/
https://ncbi.nlm.nih.gov/pubmed/23527287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059928
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