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NANOG Reporter Cell Lines Generated by Gene Targeting in Human Embryonic Stem Cells
BACKGROUND: Pluripotency and self-renewal of human embryonic stem cells (hESCs) is mediated by a complex interplay between extra- and intracellular signaling pathways, which regulate the expression of pluripotency-specific transcription factors. The homeodomain transcription factor NANOG plays a cen...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932718/ https://ncbi.nlm.nih.gov/pubmed/20824089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012533 |
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