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NANOG Reporter Cell Lines Generated by Gene Targeting in Human Embryonic Stem Cells

BACKGROUND: Pluripotency and self-renewal of human embryonic stem cells (hESCs) is mediated by a complex interplay between extra- and intracellular signaling pathways, which regulate the expression of pluripotency-specific transcription factors. The homeodomain transcription factor NANOG plays a cen...

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Detalhes bibliográficos
Main Authors: Fischer, Yvonne, Ganic, Elvira, Ameri, Jacqueline, Xian, Xiaojie, Johannesson, Martina, Semb, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932718/
https://ncbi.nlm.nih.gov/pubmed/20824089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012533
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