Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology

A number of important pluripotency regulators, including the transcription factor Nanog, are observed to fluctuate stochastically in individual embryonic stem cells. By transiently priming cells for commitment to different lineages, these fluctuations are thought to be important to the maintenance o...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Smith, Rosanna C.G., Stumpf, Patrick S., Ridden, Sonya J., Sim, Aaron, Filippi, Sarah, Harrington, Heather A., MacArthur, Ben D.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2017
Assuntos:
Cell Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479053/
https://ncbi.nlm.nih.gov/pubmed/28636920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.005
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