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Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology

A number of important pluripotency regulators, including the transcription factor Nanog, are observed to fluctuate stochastically in individual embryonic stem cells. By transiently priming cells for commitment to different lineages, these fluctuations are thought to be important to the maintenance o...

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Vydáno v:Biophys J
Hlavní autoři: Smith, Rosanna C.G., Stumpf, Patrick S., Ridden, Sonya J., Sim, Aaron, Filippi, Sarah, Harrington, Heather A., MacArthur, Ben D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479053/
https://ncbi.nlm.nih.gov/pubmed/28636920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.005
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