Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity

A number of key regulators of mouse embryonic stem (ES) cell identity, including the transcription factor Nanog, show strong expression fluctuations at the single cell level. The molecular basis for these fluctuations is unknown. Here we used a genetic complementation strategy to investigate express...

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Bibliografiset tiedot
Päätekijät: MacArthur, Ben D., Sevilla, Ana, Lenz, Michel, Müller, Franz-Josef, Schuldt, Berhard M., Schuppert, Andreas A., Ridden, Sonya J., Stumpf, Patrick S., Fidalgo, Miguel, Ma’ayan, Avi, Wang, Jianlong, Lemischka, Ihor R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507454/
https://ncbi.nlm.nih.gov/pubmed/23103910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2603
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