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Critical role of Jumonji domain of JMJD1C in MLL-rearranged leukemia
JMJD1C, a member of the lysine demethylase 3 family, is aberrantly expressed in mixed lineage leukemia (MLL) gene-rearranged (MLLr) leukemias. We have shown previously that JMJD1C is required for self-renewal of acute myeloid leukemia (AML) leukemia stem cells (LSCs) but not normal hematopoietic ste...
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| 出版年: | Blood Adv |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517669/ https://ncbi.nlm.nih.gov/pubmed/31076406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018026054 |
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