A carregar...

Modular total synthesis and cell-based anticancer activity evaluation of ouabagenin and other cardiotonic steroids with varying degrees of oxygenation.

A Cu(II)-catalyzed diastereoselective Michael/aldol cascade approach is used to accomplish concise total syntheses of cardiotonic steroids with varying degrees of oxygenation including cardenolides ouabagenin, sarmentologenin, 19-hydroxysarmentogenin, and 5-epi-panogenin. These syntheses enabled the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Khatri, Hem Raj, Bhattarai, Bijay, Kaplan, Will, Li, Zhongzheng, Curtis Long, Marcus John, Aye, Yimon, Nagorny, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516474/
https://ncbi.nlm.nih.gov/pubmed/30802047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b12870
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!