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Concise Enantioselective Total Synthesis of Cardiotonic Steroids 19-Hydroxysarmentogenin and Trewianin Aglycone

The expedient and scalable approach to cardiotonic steroids carrying oxygenation at the C11- and C19- positions has been developed and applied to the total asymmetric synthesis of steroids 19-hydroxysarmentogenin and trewianin aglycone as well as to the assembly of the panogenin core. This new appro...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Kaplan, Will, Khatri, Hem Raj, Nagorny, Pavel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015484/
https://ncbi.nlm.nih.gov/pubmed/27232585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b04029
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