Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson’s diseases

Cardiolipin (CL) is a mitochondrial signature phospholipid that is required for membrane structure, respiration, dynamics, and mitophagy. Oxidative damage of CL by reactive oxygen species is implicated in the pathogenesis of Parkinson's disease (PD), but the underlying cause remains elusive. Th...

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Bibliographic Details
Published in:Aging Cell
Main Authors: Song, Chengjie, Zhang, Jun, Qi, Shasha, Liu, Zhen, Zhang, Xiaoyang, Zheng, Yue, Andersen, John‐Paul, Zhang, Weiping, Strong, Randy, Martinez, Paul Anthony, Musi, Nicolas, Nie, Jia, Shi, Yuguang
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516155/
https://ncbi.nlm.nih.gov/pubmed/30838774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12941
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