Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson’s diseases

Cardiolipin (CL) is a mitochondrial signature phospholipid that is required for membrane structure, respiration, dynamics, and mitophagy. Oxidative damage of CL by reactive oxygen species is implicated in the pathogenesis of Parkinson's disease (PD), but the underlying cause remains elusive. Th...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Song, Chengjie, Zhang, Jun, Qi, Shasha, Liu, Zhen, Zhang, Xiaoyang, Zheng, Yue, Andersen, John‐Paul, Zhang, Weiping, Strong, Randy, Martinez, Paul Anthony, Musi, Nicolas, Nie, Jia, Shi, Yuguang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516155/
https://ncbi.nlm.nih.gov/pubmed/30838774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12941
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