Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

Oxidative stress causes mitochondrial dysfunction and metabolic complications through unknown mechanisms. Cardiolipin (CL) is a key mitochondrial phospholipid required for oxidative phosphorylation. Oxidative damage to CL from pathological remodeling is implicated in the etiology of mitochondrial dy...

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Main Authors: Li, Jia, Romestaing, Caroline, Han, Xianlin, Li, Yuan, Hao, Xinbao, Wu, Yinyuan, Sun, Chao, Jefferson, Leonard S., Xiong, Jingwei, LaNoue, Kathryn F., Chang, Zhijie, Lynch, Christopher J., Wang, Huayan, Shi, Yuguang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923392/
https://ncbi.nlm.nih.gov/pubmed/20674860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.07.003
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