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ALCAT1 Controls Mitochondrial Etiology of Fatty Liver Diseases, Linking Defective Mitophagy to Hepatosteatosis

Defective autophagy is implicated in the pathogenesis of nonalcoholic fatty liver diseases (NAFLD) through poorly defined mechanisms. Cardiolipin is a mitochondrial phospholipid required for bioenergetics and mitophagy from yeast to mammals. Here, we investigated a role for ALCAT1 in the development...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hepatology
Egile Nagusiak: Wang, Li, Liu, Xiaolei, Nie, Jia, Zhang, Jun, Kimball, Scot R., Zhang, Hai, Zhang, Weiping J., Jefferson, Leonard S., Cheng, Zeneng, Ji, Qiuhe, Shi, Yuguang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303512/
https://ncbi.nlm.nih.gov/pubmed/25203315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27420
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