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ALCAT1 Controls Mitochondrial Etiology of Fatty Liver Diseases, Linking Defective Mitophagy to Hepatosteatosis

Defective autophagy is implicated in the pathogenesis of nonalcoholic fatty liver diseases (NAFLD) through poorly defined mechanisms. Cardiolipin is a mitochondrial phospholipid required for bioenergetics and mitophagy from yeast to mammals. Here, we investigated a role for ALCAT1 in the development...

詳細記述

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書誌詳細
出版年:Hepatology
主要な著者: Wang, Li, Liu, Xiaolei, Nie, Jia, Zhang, Jun, Kimball, Scot R., Zhang, Hai, Zhang, Weiping J., Jefferson, Leonard S., Cheng, Zeneng, Ji, Qiuhe, Shi, Yuguang
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303512/
https://ncbi.nlm.nih.gov/pubmed/25203315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27420
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