ALCAT1 Controls Mitochondrial Etiology of Fatty Liver Diseases, Linking Defective Mitophagy to Hepatosteatosis

Defective autophagy is implicated in the pathogenesis of nonalcoholic fatty liver diseases (NAFLD) through poorly defined mechanisms. Cardiolipin is a mitochondrial phospholipid required for bioenergetics and mitophagy from yeast to mammals. Here, we investigated a role for ALCAT1 in the development...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Hepatology
Hauptverfasser: Wang, Li, Liu, Xiaolei, Nie, Jia, Zhang, Jun, Kimball, Scot R., Zhang, Hai, Zhang, Weiping J., Jefferson, Leonard S., Cheng, Zeneng, Ji, Qiuhe, Shi, Yuguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303512/
https://ncbi.nlm.nih.gov/pubmed/25203315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27420
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge