Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis

BACKGROUND & AIMS: Obesity promotes the development of nonalcoholic fatty liver diseases (NAFLDs), yet not all obese patients develop NAFLD. The underlying causes for this discrepancy remain elusive. LPGAT1 is an acyltransferase that catalyzes the remodeling of phosphatidylglycerol (PG), a mitoc...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Zhang, Xiaoyang, Zhang, Jun, Sun, Haoran, Liu, Xueling, Zheng, Yue, Xu, Dan, Wang, Jianing, Jia, Dandan, Han, Xianlin, Liu, Feng, Nie, Jia, Shi, Yuguang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463126/
https://ncbi.nlm.nih.gov/pubmed/30831319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.02.002
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