Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis

BACKGROUND & AIMS: Obesity promotes the development of nonalcoholic fatty liver diseases (NAFLDs), yet not all obese patients develop NAFLD. The underlying causes for this discrepancy remain elusive. LPGAT1 is an acyltransferase that catalyzes the remodeling of phosphatidylglycerol (PG), a mitoc...

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Bibliografiset tiedot
Julkaisussa:Cell Mol Gastroenterol Hepatol
Päätekijät: Zhang, Xiaoyang, Zhang, Jun, Sun, Haoran, Liu, Xueling, Zheng, Yue, Xu, Dan, Wang, Jianing, Jia, Dandan, Han, Xianlin, Liu, Feng, Nie, Jia, Shi, Yuguang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2019
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463126/
https://ncbi.nlm.nih.gov/pubmed/30831319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.02.002
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