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Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma
Rationale: Extracellular DNA (eDNA) and neutrophil extracellular traps (NETs) are implicated in multiple inflammatory diseases. NETs mediate inflammasome activation and IL-1β secretion from monocytes and cause airway epithelial cell injury, but the role of eDNA, NETs, and IL-1β in asthma is uncertai...
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| Udgivet i: | Am J Respir Crit Care Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6515873/ https://ncbi.nlm.nih.gov/pubmed/30888839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201810-1869OC |
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