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Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

Rationale: Extracellular DNA (eDNA) and neutrophil extracellular traps (NETs) are implicated in multiple inflammatory diseases. NETs mediate inflammasome activation and IL-1β secretion from monocytes and cause airway epithelial cell injury, but the role of eDNA, NETs, and IL-1β in asthma is uncertai...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Crit Care Med
Prif Awduron: Lachowicz-Scroggins, Marrah E., Dunican, Eleanor M., Charbit, Annabelle R., Raymond, Wilfred, Looney, Mark R., Peters, Michael C., Gordon, Erin D., Woodruff, Prescott G., Lefrançais, Emma, Phillips, Brenda R., Mauger, David T., Comhair, Suzy A., Erzurum, Serpil C., Johansson, Mats W., Jarjour, Nizar N., Coverstone, Andrea M., Castro, Mario, Hastie, Annette T., Bleecker, Eugene R., Fajt, Merritt L., Wenzel, Sally E., Israel, Elliot, Levy, Bruce D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515873/
https://ncbi.nlm.nih.gov/pubmed/30888839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201810-1869OC
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