Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids

BACKGROUND: Airway type 2 inflammation is usually corticosteroid sensitive, but the role of type 2 inflammation as a mechanism of asthma in patients receiving high-dose inhaled corticosteroids (ICSs) is uncertain. OBJECTIVE: We sought to determine whether airway type 2 inflammation persists in patie...

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Gepubliceerd in:J Allergy Clin Immunol
Hoofdauteurs: Peters, Michael C., Kerr, Sheena, Dunican, Eleanor M., Woodruff, Prescott G., Fajt, Merritt L., Levy, Bruce D., Israel, Elliot, Phillips, Brenda R., Mauger, David T., Comhair, Suzy A., Erzurum, Serpil C., Johansson, Mats W., Jarjour, Nizar N., Coverstone, Andrea M., Castro, Mario, Hastie, Annette T., Bleecker, Eugene R., Wenzel, Sally E., Fahy, John V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128784/
https://ncbi.nlm.nih.gov/pubmed/29524537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.12.1009
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