A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Elucidation of mechanisms underlying the increased androgen receptor (AR) activity and subsequent development of aggressive prostate cancer (PrCa) is pivotal in developing new therapies. Using a systems biology approach, we interrogated the AR-regulated proteome and identified PDZ binding kinase (PB...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogene
Prif Awduron: Warren, Anne Y., Massie, Charlie E., Watt, Kate, Luko, Katarina, Orafidiya, Folake, Selth, Luke A., Mohammed, Hisham, Chohan, Brinder S., Menon, Suraj, Baridi, Ajoeb, Zhao, Wanfeng, Escriu, Carles, Pungsrinont, Thanakorn, D’Santos, Clive, Yang, Xiaoping, Taylor, Chris, Qureshi, Arham, Zecchini, Vincent R., Shaw, Greg L., Dehm, Scott M., Mills, Ian G., Carroll, Jason S., Tilley, Wayne D., McEwan, Iain J., Baniahmad, Aria, Neal, David E., Asim, Mohammad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514849/
https://ncbi.nlm.nih.gov/pubmed/30237440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0501-z
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg