Senolytic compounds control a distinct fate of androgen receptor agonist- and antagonist-induced cellular senescent LNCaP prostate cancer cells

BACKGROUND: The benefit of inducing cellular senescence as a tumor suppressive strategy remains questionable due to the senescence-associated secretory phenotype. Hence, studies and development of senolytic compounds that induce cell death in senescent cells have recently emerged. Senescent cells ar...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Pungsrinont, Thanakorn, Sutter, Malika Franziska, Ertingshausen, Maren C. C. M., Lakshmana, Gopinath, Kokal, Miriam, Khan, Amir Saeed, Baniahmad, Aria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183592/
https://ncbi.nlm.nih.gov/pubmed/32351687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00422-2
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