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XPG-related nucleases are hierarchically recruited for double-stranded rDNA break resection
dsDNA breaks (DSBs) are resected in a 5′→3′ direction, generating single-stranded DNA (ssDNA). This promotes DNA repair by homologous recombination and also assembly of signaling complexes that activate the DNA damage checkpoint effector kinase Chk1. In fission yeast (Schizosaccharomyces pombe), gen...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514642/ https://ncbi.nlm.nih.gov/pubmed/30885940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005415 |
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