The extracellular domain of epithelial cell adhesion molecule (EpCAM) enhances multipotency of mesenchymal stem cells through EGFR–LIN28–LET7 signaling

Mesenchymal stem cells (MSCs) are widely considered to be an attractive cell source for regenerative therapies, but maintaining multipotency and self-renewal in cultured MSCs is especially challenging. Hence, the development and mechanistic description of strategies that help promote multipotency in...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Kuan, I.-I., Lee, Chi-Chiu, Chen, Chien-Hsu, Lu, Jean, Kuo, Yuan-Sung, Wu, Han-Chung
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514611/
https://ncbi.nlm.nih.gov/pubmed/30926604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007386
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