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EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion

Cell-surface tumor marker EpCAM plays a key role in proliferation, differentiation and adhesion processes in stem and epithelial cells. It is established as a cell-cell adhesion molecule, forming intercellular interactions through homophilic association. However, the mechanism by which such interact...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Gaber, Aljaž, Kim, Seung Joong, Kaake, Robyn M., Benčina, Mojca, Krogan, Nevan, Šali, Andrej, Pavšič, Miha, Lenarčič, Brigita
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125409/
https://ncbi.nlm.nih.gov/pubmed/30185875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31482-7
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