EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers

Head and neck squamous cell carcinomas (HNSCCs) are characterized by outstanding molecular heterogeneity that results in severe therapy resistance and poor clinical outcome. Inter- and intratumoral heterogeneity in epithelial-mesenchymal transition (EMT) was recently revealed as a major parameter of...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Pan, Min, Schinke, Henrik, Luxenburger, Elke, Kranz, Gisela, Shakhtour, Julius, Libl, Darko, Huang, Yuanchi, Gaber, Aljaž, Pavšič, Miha, Lenarčič, Brigita, Kitz, Julia, Jakob, Mark, Schwenk-Zieger, Sabina, Canis, Martin, Hess, Julia, Unger, Kristian, Baumeister, Philipp, Gires, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177200/
https://ncbi.nlm.nih.gov/pubmed/30261040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006624
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