Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer

DUSP6/MKP3 is a dual-specific phosphatase that regulates extracellular regulated kinase ERK1/2 and ERK5 activity, with an increasingly recognized role as tumor suppressor. In silico studies from Gene expression Omnibus (GEO) and Cancer Genome atlas (TCGA) databases reveal poor prognosis in those Non...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Moncho-Amor, Verónica, Pintado-Berninches, Laura, Ibañez de Cáceres, Inmaculada, Martín-Villar, Ester, Quintanilla, Miguel, Chakravarty, Probir, Cortes-Sempere, María, Fernández-Varas, Beatriz, Rodriguez-Antolín, Carlos, de Castro, Javier, Sastre, Leandro, Perona, Rosario
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514584/
https://ncbi.nlm.nih.gov/pubmed/31027181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20082036
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