High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response

The elucidation of mechanisms involved in resistance to therapies is essential to improve the survival of patients with malignant gliomas. A major feature possessed by glioma cells that may aid their ability to survive therapy and reconstitute tumors is the capacity for self-renewal. We show here th...

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Udgivet i:Oncogenesis
Main Authors: Arrizabalaga, Olatz, Moreno-Cugnon, Leire, Auzmendi-Iriarte, Jaione, Aldaz, Paula, Ibanez de Caceres, Inmaculada, Garros-Regulez, Laura, Moncho-Amor, Veronica, Torres-Bayona, Sergio, Pernía, Olga, Pintado-Berninches, Laura, Carrasco-Ramirez, Patricia, Cortes-Sempere, María, Rosas, Rocío, Sanchez-Gomez, Pilar, Ruiz, Irune, Caren, Helena, Pollard, Steven, Garcia, Idoia, Sacido, Angel-Ayuso, Lovell-Badge, Robin, Belda-Iniesta, Cristobal, Sampron, Nicolas, Perona, Rosario, Matheu, Ander
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865544/
https://ncbi.nlm.nih.gov/pubmed/29284798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0003-9
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