Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling

Signaling of the pleiotropic cytokine Interleukin-6 (IL-6) via its soluble IL-6R (sIL-6R) has been termed trans-signaling and is thought to be responsible for the pro-inflammatory properties of IL-6. The sIL-6R can be generated by alternative mRNA splicing or proteolytic cleavage of the membrane-bou...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Flynn, Charlotte M., Garbers, Yvonne, Lokau, Juliane, Wesch, Daniela, Schulte, Dominik M., Laudes, Matthias, Lieb, Wolfgang, Aparicio-Siegmund, Samadhi, Garbers, Christoph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513869/
https://ncbi.nlm.nih.gov/pubmed/31086276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43617-5
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