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The length of the interleukin-11 receptor stalk determines its capacity for classic signaling

Interleukin (IL)-11 is a multifunctional cytokine that was traditionally recognized for its hematopoietic and anti-inflammatory functions, but has recently been shown also to be involved in tumorigenesis. IL-11 signaling is initiated by binding of the cytokine to the IL-11 receptor (IL-11R), which i...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lokau, Juliane, Garbers, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925790/
https://ncbi.nlm.nih.gov/pubmed/29523682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001879
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