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The length of the interleukin-11 receptor stalk determines its capacity for classic signaling
Interleukin (IL)-11 is a multifunctional cytokine that was traditionally recognized for its hematopoietic and anti-inflammatory functions, but has recently been shown also to be involved in tumorigenesis. IL-11 signaling is initiated by binding of the cytokine to the IL-11 receptor (IL-11R), which i...
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| Published in: | J Biol Chem |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5925790/ https://ncbi.nlm.nih.gov/pubmed/29523682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001879 |
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