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Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling
Signaling of the pleiotropic cytokine Interleukin-6 (IL-6) via its soluble IL-6R (sIL-6R) has been termed trans-signaling and is thought to be responsible for the pro-inflammatory properties of IL-6. The sIL-6R can be generated by alternative mRNA splicing or proteolytic cleavage of the membrane-bou...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6513869/ https://ncbi.nlm.nih.gov/pubmed/31086276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43617-5 |
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