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BET Inhibitors Reduce Cell Size and Induce Reversible Cell Cycle Arrest in AML
Inhibitors of the bromodomain and extra-terminal domain family (BETi) offer a new approach to treating hematological malignancies, with leukemias containing MLL rearrangements being especially sensitive due to a reliance on the regulation of transcription elongation. We explored the mechanism of act...
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| Publicat a: | J Cell Biochem |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6513713/ https://ncbi.nlm.nih.gov/pubmed/30417424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.28005 |
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