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Integrating Combinatorial Lipid Nanoparticle and Chemically Modified Protein for Intracellular Delivery and Genome Editing

The use of protein to precisely manipulate cell signaling is an effective approach for controlling cell fate and developing precision medicine. More recently, programmable nucleases, such as CRISPR/Cas9, have shown extremely high potency for editing genetic flow of mammalian cells, and for treating...

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Detalhes bibliográficos
Publicado no:Acc Chem Res
Main Authors: Chang, Jin, Chen, Xianghan, Glass, Zachary, Gao, Feng, Mao, Lanqun, Wang, Ming, Xu, Qiaobing
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513672/
https://ncbi.nlm.nih.gov/pubmed/30586281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.8b00493
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