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ALTHEA Gold Libraries™: antibody libraries for therapeutic antibody discovery
We describe here the design, construction and validation of ALTHEA Gold Libraries™. These single-chain variable fragment (scFv), semisynthetic libraries are built on synthetic human well-known IGHV and IGKV germline genes combined with natural human complementarity-determining region (CDR)-H3/J(H) (...
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| Pubblicato in: | MAbs |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512909/ https://ncbi.nlm.nih.gov/pubmed/30663541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1571879 |
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