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Discovery of internalizing antibodies to tumor antigens from phage libraries

Phage antibody technology can be used to generate human antibodies to essentially any antigen. Many therapeutic target antigens are cell surface receptors, which can be challenging targets for antibody generation. In addition, for many therapeutic applications, one needs antibodies that not only bin...

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Detalhes bibliográficos
Main Authors: Zhou, Yu, Marks, James D
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180867/
https://ncbi.nlm.nih.gov/pubmed/22208981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-416039-2.00003-3
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