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Structural characterization of monoclonal antibodies targeting C-terminal Ser(404) region of phosphorylated tau protein
Targeting tau with immunotherapies is currently the most common approach taken in clinical trials of patients with Alzheimer’s disease. The most prominent pathological feature of tau is its hyperphosphorylation, which may cause the protein to aggregate into toxic assemblies that collectively lead to...
Guardat en:
| Publicat a: | MAbs |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512906/ https://ncbi.nlm.nih.gov/pubmed/30794086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1574530 |
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