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Increasing Cytosine Base Editing Scope and Efficiency With Engineered Cas9-PmCDA1 Fusions and the Modified sgRNA in Rice

Base editors that do not require double-stranded DNA cleavage or homology-directed repair enable higher efficiency and cleaner substitution of targeted single nucleotides in genomic DNA than conventional approaches. However, their broad applications are limited within the editing window of several b...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Genet
Main Authors: Wu, Ying, Xu, Wen, Wang, Feipeng, Zhao, Si, Feng, Feng, Song, Jinling, Zhang, Chengwei, Yang, Jinxiao
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512751/
https://ncbi.nlm.nih.gov/pubmed/31134125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00379
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