Increasing Cytosine Base Editing Scope and Efficiency With Engineered Cas9-PmCDA1 Fusions and the Modified sgRNA in Rice

Base editors that do not require double-stranded DNA cleavage or homology-directed repair enable higher efficiency and cleaner substitution of targeted single nucleotides in genomic DNA than conventional approaches. However, their broad applications are limited within the editing window of several b...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Genet
Egile Nagusiak: Wu, Ying, Xu, Wen, Wang, Feipeng, Zhao, Si, Feng, Feng, Song, Jinling, Zhang, Chengwei, Yang, Jinxiao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Genetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512751/
https://ncbi.nlm.nih.gov/pubmed/31134125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00379
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