Defective Renal Angiotensin III and AT(2) Receptor Signaling in Prehypertensive Spontaneously Hypertensive Rats

BACKGROUND: Previous studies demonstrated that angiotensin (Ang) III, not Ang II, is the predominant endogenous agonist for Ang type‐2 receptor (AT (2)R)‐induced natriuresis in normal rats, and that hypertensive 12‐week‐old spontaneously hypertensive rats (SHR) lack natriuretic responses to Ang III....

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書目詳細資料
發表在:J Am Heart Assoc
Main Authors: Kemp, Brandon A., Howell, Nancy L., Keller, Susanna R., Gildea, John J., Shao, Weijian, Navar, Luis Gabriel, Carey, Robert M.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512109/
https://ncbi.nlm.nih.gov/pubmed/31039659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.012016
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