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AT(2) Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II-Dependent Hypertension
RATIONALE: Compound 21 (C-21) is a highly selective non-peptide angiotensin AT(2) receptor (AT(2)R) agonist. OBJECTIVE: To test the hypothesis that chronic AT(2)R activation with C-21 induces natriuresis via an action at the renal proximal tubule (RPT) and lowers blood pressure (BP) in experimental...
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| Publicado no: | Circ Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975636/ https://ncbi.nlm.nih.gov/pubmed/27323774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308384 |
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