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Intrarenal ghrelin receptor inhibition ameliorates angiotensin II-dependent hypertension in rats
The intrarenal ghrelin receptor (GR) is localized to collecting duct (CD) cells, where it increases epithelial Na(+) channel (αE(Na)C)-dependent sodium reabsorption in rodents. We hypothesized that chronic GR inhibition with intrarenal GR siRNA lowers blood pressure (BP) in angiotensin II-dependent...
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| Izdano u: | Am J Physiol Renal Physiol |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6230753/ https://ncbi.nlm.nih.gov/pubmed/29923768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00010.2018 |
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