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At(2) Receptor Activation Induces Natriuresis and Lowers Blood Pressure
RATIONALE: Compound 21 (C-21) is a highly selective non-peptide AT(2) receptor (AT(2)R) agonist. OBJECTIVE: To test the hypothesis that renal proximal tubule AT(2)Rs induce natriuresis and lower blood pressure (BP) in Sprague-Dawley rats and mice. METHODS AND RESULTS: In rats, AT(2)R activation with...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116673/ https://ncbi.nlm.nih.gov/pubmed/24903104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.304110 |
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