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Macrocycles as Protein-Protein Interaction Inhibitors

Macrocyclic compounds such as cyclic peptides have emerged as a new and exciting class of drug candidates for inhibition of intracellular protein-protein interactions, which are challenging targets for conventional drug modalities (i.e., small molecules and proteins). Over the past decade, several c...

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Détails bibliographiques
Publié dans:Biochem J
Auteurs principaux: Dougherty, Patrick G., Qian, Ziqing, Pei, Dehua
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511976/
https://ncbi.nlm.nih.gov/pubmed/28298556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160619
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