HMGB1 regulates erastin-induced ferroptosis via RAS-JNK/p38 signaling in HL-60/NRAS(Q61L) cells

Ferroptosis is emerging as a new form of regulated cell death driven by oxidative injury promoting lipid peroxidation in an iron-dependent manner. High mobility group box 1 (HMGB1) plays an important role in leukemia pathogenesis and chemotherapy resistance. The mechanisms of ferroptosis in tumor pa...

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Publicat a:Am J Cancer Res
Autors principals: Ye, Fanghua, Chai, Wenwen, Xie, Min, Yang, Minghua, Yu, Yan, Cao, Lizhi, Yang, Liangchun
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511643/
https://ncbi.nlm.nih.gov/pubmed/31105999
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