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HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells
BACKGROUND: Sodium/iodide symporter (NIS)-mediated iodide uptake plays an important physiological role in regulating thyroid gland function, as well as in diagnosing and treating Graves’ disease and thyroid cancer. High-mobility group box 1 (HMGB1), a highly conserved nuclear protein, is a positive...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6647330/ https://ncbi.nlm.nih.gov/pubmed/31331356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1328-3 |
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