Structural and Functional Studies of Bacterial Enolase, a Potential Target Against Gram-Negative Pathogens.

Enolase is a glycolytic metalloenzyme involved in carbon metabolism. The advantage of targeting enolase lies in its essentiality in many biological processes such as cell wall formation, RNA turnover and as a plasminogen receptor. We initially used a DARTS assay to identify enolase as a target in Es...

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Publicado en:Biochemistry
Main Authors: Krucinska, Jolanta, Falcone, Eric, Erlandsen, Heidi, Hazeen, Akram, Lombardo, Michael N., Estrada, Alexavier, Robinson, Victoria, Anderson, Amy C., Wright, Dennis L.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511404/
https://ncbi.nlm.nih.gov/pubmed/30714720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01298
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