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Structural and Functional Studies of Bacterial Enolase, a Potential Target Against Gram-Negative Pathogens.
Enolase is a glycolytic metalloenzyme involved in carbon metabolism. The advantage of targeting enolase lies in its essentiality in many biological processes such as cell wall formation, RNA turnover and as a plasminogen receptor. We initially used a DARTS assay to identify enolase as a target in Es...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511404/ https://ncbi.nlm.nih.gov/pubmed/30714720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01298 |
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