Donor killer-cell immunoglobulin-like receptor (KIR) genotype does not improve graft-versus-leukemia responses in chronic lymphocytic leukemia (CLL) after unrelated donor transplant: a CIBMTR analysis

Allogeneic hematopoietic cell transplantation (alloHCT) remains the sole curative therapy for patients with CLL leading to 40–45% long-term survival. The impact of donor KIR genotype on outcomes of unrelated donor (URD) alloHCT for CLL is unknown. METHODS: We examined 573 adult (URD)-CLL recipient p...

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Pubblicato in:Biol Blood Marrow Transplant
Autori principali: Bachanova, Veronika, Weisdorf, Daniel J., Wang, Tao, Marsh, Steven G.E., Cereb, Nezih, Haagenson, Michael D, Spellman, Stephen R., Lee, Stephanie J., Guethlein, Lisbeth A., Parham, Peter, Miller, Jeffrey S., Cooley, Sarah A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511301/
https://ncbi.nlm.nih.gov/pubmed/30594542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2018.12.763
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