Donor killer-cell immunoglobulin-like receptor B haplotypes, recipient HLA-C1 and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia()

Killer cell immunoglobulin-like receptors (KIR) interact with HLA class I ligands to regulate NK cell development and function. These interactions affect the outcome of unrelated donor (URD) hematopoietic cell transplantation (HCT). We have shown previously that donors with KIR B vs. KIR A haplotype...

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Main Authors: Cooley, Sarah, Weisdorf, Daniel J., Guethlein, Lisbeth A., Klein, John P., Wang, Tao, Marsh, Steven G.E., Spellman, Stephen, Haagenson, Michael D., Saeturn, Koy, Ladner, Martha, Trachtenberg, Elizabeth, Parham, Peter, Miller, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031316/
https://ncbi.nlm.nih.gov/pubmed/24748496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302517
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